Taking a quick inventory of the things that might be responsible for your fatigue is the first step toward relief. In general, most cases of fatigue may be attributed to three areas: lifestyle factors, medical conditions or psychological problems.

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Lifestyle Factors

Feelings of fatigue often have an obvious cause, such as:

  • Alcohol use or abuse
  • Caffeine use
  • Excessive physical activity
  • Inactivity
  • Lack of sleep
  • Medications, such as antihistamines, cough medicines and cold remedies
  • Unhealthy eating habits

Psychological Conditions

Fatigue is a common symptom of mental health problems, such as:

  • Anxiety
  • Depression
  • Grief
  • Stress

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Medical Conditions

Unrelenting exhaustion may be a sign of a medical condition or underlying illness, such as:

  • Acute liver failure
  • Anemia
  • Cancer
  • Chronic fatigue syndrome
  • Chronic kidney disease
  • COPD (Chronic Obstructed Pulmonary Disease)
  • Emphysema
  • Heart disease
  • Hyperthyroidism (overactive thyroid)
  • Hypothyroidism (a thyroid disorder)
  • Medications, such as prescription pain medications, heart medications, blood pressure medications and some antidepressants
  • Obesity
  • Restless legs syndrome
  • Sleep apnea
  • Type 1 diabetes
  • Type 2 diabetes

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